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I-BRD9(Cat No.:I002236)is a selective chemical inhibitor of BRD9, a bromodomain-containing protein within the ncBAF chromatin-remodeling complex. By blocking BRD9’s ability to recognize acetylated histones, I-BRD9 disrupts transcriptional programs involved in cell identity, proliferation, and oncogenic
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Selleck Chemicals
i brd9 I Brd9, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/i+brd9/pmc11919606-43-0-2?v=Selleck+Chemicals Average 93 stars, based on 1 article reviews
i brd9 - by Bioz Stars,
2026-08
93/100 stars
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Tocris
i brd9 ![]() I Brd9, supplied by Tocris, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/i+brd9/pmc05536025-143-0-1?v=Tocris Average 90 stars, based on 1 article reviews
i brd9 - by Bioz Stars,
2026-08
90/100 stars
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DiscoverX corporation
brd9 binder ![]() Brd9 Binder, supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/i+brd9/pmc04885110-16-33-55?v=DiscoverX+corporation Average 90 stars, based on 1 article reviews
brd9 binder - by Bioz Stars,
2026-08
90/100 stars
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Merck KGaA
brd9 inhibitor i-brd9 sml1534 ![]() Brd9 Inhibitor I Brd9 Sml1534, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/i+brd9/pmc11518989__41375_2024_2379_MOESM1_ESM-122-10-19?v=Merck+KGaA Average 90 stars, based on 1 article reviews
brd9 inhibitor i-brd9 sml1534 - by Bioz Stars,
2026-08
90/100 stars
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Verlag GmbH
bromodomain probe i-brd9 ![]() Bromodomain Probe I Brd9, supplied by Verlag GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/i+brd9/10__1002_slash_ange__201611281-42-18-7?v=Verlag+GmbH Average 90 stars, based on 1 article reviews
bromodomain probe i-brd9 - by Bioz Stars,
2026-08
90/100 stars
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Glaxo Smith
brd9 ![]() Brd9, supplied by Glaxo Smith, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/i+brd9/10__1002_slash_anie__201611281-45-25-28?v=Glaxo+Smith Average 86 stars, based on 1 article reviews
brd9 - by Bioz Stars,
2026-08
86/100 stars
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I-BRD9 is developed from thienopyridone scaffold. It can also be used as an identifier for BRD9 regulated gene in Kasumi-1 cells involved in oncology and immune response pathways.
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I-BRD9 is a selective cellular chemical probe of bromodomain-containing protein 9 (BRD9) with pIC50 value of 7.3 μM. I-BRD9 has high selectivity for bromodomain and extra terminal domain (BET) family and highly homologous bromodomain-containing protein
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Image Search Results
Journal: International Journal of Molecular Sciences
Article Title: BRD9 Inhibition, Alone or in Combination with Cytostatic Compounds as a Therapeutic Approach in Rhabdoid Tumors
doi: 10.3390/ijms18071537
Figure Lengend Snippet: Half maximal inhibitory concentrations (IC 50 ) of BI-9564 and I-BRD9 in RT cell lines incubated for 72 or 144 h. Cell proliferation was evaluated by MTT cytotoxicity assays. ( n ≥ 3).
Article Snippet:
Techniques: Incubation
Journal: International Journal of Molecular Sciences
Article Title: BRD9 Inhibition, Alone or in Combination with Cytostatic Compounds as a Therapeutic Approach in Rhabdoid Tumors
doi: 10.3390/ijms18071537
Figure Lengend Snippet: Percentage of cells in G1 cell cycle phase after incubating with BI-9564 and I-BRD9 at the indicated concentrations for 72 h. ( n ≥ 3; mean ± SD; * treatment vs. control with p < 0.05, one-way ANOVA).
Article Snippet:
Techniques: Control
Journal: International Journal of Molecular Sciences
Article Title: BRD9 Inhibition, Alone or in Combination with Cytostatic Compounds as a Therapeutic Approach in Rhabdoid Tumors
doi: 10.3390/ijms18071537
Figure Lengend Snippet: Percentage of dead RT cells after incubation with different BI-9564 and I-BRD9 concentrations for 72 h. ( n ≥ 3; mean ± SD, * treatment vs. control with p < 0.05, one-way ANOVA).
Article Snippet:
Techniques: Incubation, Control
Journal: International Journal of Molecular Sciences
Article Title: BRD9 Inhibition, Alone or in Combination with Cytostatic Compounds as a Therapeutic Approach in Rhabdoid Tumors
doi: 10.3390/ijms18071537
Figure Lengend Snippet: IC 50 and combination indices (CI) of combined treatments. Treatment of BT12 and G401 with combinations of I-BRD9 and three cytotoxic drugs for 72 h. CI < 1 indicates synergistic effects and CI > 1 antagonistic effects of combined drugs. R 2 represents the determination coefficient of linear regression in median effect plot. ( n ≥ 3).
Article Snippet:
Techniques: